Selected Publications


(a)        Journals

Chan YK, Estaki M, & Gibson DL, (2013) Clinical consequences of diet-induced dysbiosis of the intestinal microbiota. Annales Nestlé Annals of Nutrition and Metabolism. doi:10.1159/000354902

Sham HP, Yu EY, Gulen MF, Bhinder G, Stahl M, Chan JM, Brewster L, Morampudi V, & Gibson DL, Hughes MR, McNagny KM, Li X, Vallance BA. (2013) SIGIRR, a Negative Regulator of TLR/IL-1R Signalling Promotes Microbiota Dependent Resistance to Colonization by Enteric Bacterial Pathogens. PLoS Pathog.9(8):e1003539

Botta A, Laher I, Beam J, Decoffe D, Brown K, Halder S, Devlin A, Gibson DL, & Ghosh S. (2013) Short Term Exercise Induces PGC-1α, Ameliorates Inflammation and Increases Mitochondrial Membrane Proteins but Fails to Increase Respiratory Enzymes in Aging Diabetic Hearts.PLoS One. 8(8):e70248

Madeira JM, Renschler CJ, Mueller B, Hashioka S, Gibson DL, & Klegeris A. (2013) Novel protective properties of auranofin: Inhibition of human astrocyte cytotoxic secretions and direct neuroprotection. Life Sci. doi:pii: S0024-3205(13)00220-8

Ghosh S, DeCoffe D, Brown K, Rajendiran E, Estaki M, Dai C, Yip A, Gibson DL. (2013) Fish oil attenuates omega-6 polyunsaturated fatty acid-induced dysbiosis and infectious colitis but impairs LPS dephosphorylation activity causing sepsis. PLOS One; 8(2):e55468

Ghosh S, Molcan E, Decoffe D, Dai C, Gibson DL (2013) Diets rich in ω-6 polyunsaturated fatty acids induce intestinal microbial dysbiosis in aged mice. British Journal of Nutrition. 8:1-9

Madeira JM, Gibson DL, Kean WF, Klegeris A. (2012) The biological activity of auranofin: implications for novel treatment of diseases. Inflammopharmacology. 20(6):297-306

Baker J., Brown K., Dai C., Molcan E., Chittick, S.A., Rajendiran E., Ghosh S., Mahmoud S., and D. L. Gibson (2012) Medicinal lavender modulates the enteric microflora to protect against Citrobacter rodentium-induced colitis. Am J Physiol Gastrointest Liver Physiol. 303(7):G825-36

Brown K*, DeCoffe D*, Molcan E,& Gibson, D.L..(2012) Diet-induced dysbiosis of the intestinal microbiota and the effect on immunity and disease. Nutrients. 4(8):1095-1119.

Ghosh S.,Dai C., Brown K., Rajendiran E., Makarenko S., Baker J., Ma C., Halder S., Montero M., Ionescu V.A., Klegeris A., Vallance B. A., and D. L. Gibson (2011) Colonic microbiota alters host susceptibility to infectious colitis by modulating inflammation, redox status and ion transporter gene expression American Journal of Physiology: Gastrointestinal and Liver Physiology. 301(1):G39-49.

Gibson, D.L., Montero M., Ropeleski M.J, Bergstrom K.S.B., Ma C., Ghosh, S., Merkens H., Huang T., Mansson L.M., Sham H.P., McNagny K.M, and B. A. Vallance. (2010) Interleukin-11 Reduces Toll-Like Receptor (TLR)4-Induced Colitis in TLR2-Deficient Mice and Restores Intestinal STAT3 Signaling. Gastroenterology. 139:1277-1288.

Lee, A.S.,* Gibson, D.L.,* Zhang, Y., Sham, H.P., Vallance, B.A. and J. P. Dutz (2010) Gut Barrier Disruption by an Enteric Bacterial Pathogen Accelerates Insulitis in NOD Mice. Diabetologia. 53, 741-8.

*; co-first authors

Bergstrom,K.S.B., Kissoon-Singh V., Gibson, D.L., Ma, C., Montero, M., Sham, H.P., Ryz, N., Huang, H.,Velcich, A., Finlay, B. B., Chadee, K. and B.A. Vallance (2010) Muc2 Protects Against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa. PLoS Pathogen. 6 (5):e1000902.

Gibson, D.L., Montero, M., Ryz, T. and B. A. Vallance (2009) Innate Immunity and Microbes: Conversations with the Gut Leading to Intestinal Tissue Repair and Fibrosis. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 8 (3): 228-247.

Gibson, D.L. and B.A. Vallance (2008) The intestinal microbiota is transiently altered during Salmonella induced gastroenteritis. Expert Reviews in Gastroenterology and Hepatology. 2(4): 525-9.

Gibson, D.L., Ma, C., Rosenberger, C.M., Bergstrom, K.S.B., Valdez, Y., Huang, J.T., Khan, M.A.and B. A. Vallance (2008)Toll-like Receptor 2 plays a critical role in maintaining mucosal integrity during Citrobacter rodentium induced colitis. Cellular Microbiology. 10 (2): 388-403.

Gibson, D.L., Ma, C., Bergstrom, K.S.B., Huang, J. T., Mann, C. and B. A. Vallance (2008) MyD88 mediated responses maintain intestinal homeostasis during C. rodentium induced colitis. Cellular Microbiology. 10 (3): 618-631.

Crawford, R.W., Gibson, D.L., Kay, W.W. and J.S. Gunn. (2008) Identification of a bile induced exopolysaccharide required for Salmonella biofilm formation on gallstone surfaces.Infection and Immunity.76(11):5341-9.

Ga-Mor, O., Gibson, D.L., Baluta, D., Vallance, B.V. and B.B. Finlay. (2008) A novel secretion system of Salmonella enterica acts as a virulence modulator during salmonellosis. PLoS Pathogen 4 (4): e1000036.

Khan, M.A., Bouzari, S., Ma, C., Rosenberger, C.M., Bergstrom, K.S., Gibson, D.L., Steiner, T.S., and B.A. Vallance. (2008) Flagellin-dependent and -independent inflammatory responses following infection by enteropathogenic Escherichia coli and Citrobacter rodentium. Infection and Immunity. 76(4): 1410-22.

White, A.P., Gibson, D.L., Grassl, G.A., Kay, W.W., Finlay, B.B., Vallance, B.A. and M.G. Surette (2008) Aggregation via the rdar morphotype is not a virulence adaptation in Salmonella. Infection and Immunity. 76(3): 1048-58.

Bergstrom, K. S.B., Guttman, J.A., Ma, C., Khan, M.A., Gibson, D.L., Vogl, W. and B.A. Vallance. (2008) Modulation of intestinal goblet cell numbers and function during infection by an attaching and effacing bacterial pathogen. Infection and Immunity. 76 (2): 796-811.

Gibson, D.L., White, A.P., Rajotte, C.M. and W.W. Kay (2007) AgfC and AgfE facilitate extracellular thin aggregative fimbriae in Salmonella. Microbiology. 153 (4):1131-40.

Barak, J.D., Jahn, E.J., Gibson, D.L. and A.O. Charkowski.(2007) The role of cellulose and O-Ag capsule in the colonization of plants by Salmonella enterica. Molecular Plant Microbe Interactions. 20 (9):1083-91.

Gibson, D.L., White, A.P., Snyder, S.D., Martin, S., Heiss, C., Azadi, P., Surette, M.G. and W.W. Kay (2006) Salmonella produces an O-Antigen capsule regulated by AgfD and important for environmental persistence. Journal of Bacteriology. 188 (22): 7722-30.

Snyder, S.D., Gibson, D., Heiss, C., Kay, W. and P. Azadi. (2006) Structure of a capsular polysaccharide isolated from Salmonella enteritidis. Carbohydrate Research. 341:2388-97.

White, A.P., Gibson, D.L., Kim, W., Kay, W. W. and M.G. Surette. (2006) Thin aggregative fimbriae and cellulose enhance long-term survival and persistence of Salmonella. Journal of Bacteriology. 188: 3219- 3227.

White, A.P., Gibson, D.L., Collinson, S.K., Halverson, J., Banser, P.A. and W.W. Kay. (2003) Extracellular Polysaccharides Associated with Thin Aggregative Fimbriae of Salmonella enterica serovar Enteritidis. Journal of Bacteriology. 185: 5398-5407.

White, A.P., Collinson, S.K., Banser, P.A., Gibson, D.L., Paetzel, M., Strynadka, N.C.J. and W.W. Kay. (2001) Structure and Characterization of AgfB from Salmonella enteritidis Thin Aggregative Fimbriae. Journal of Molecular Biology. 311: 735-749.


(a)        Chapters

Estaki M, Quin C, Gibson D.L. (2015) “Diet And Dysbiosis” in Luigi Nibali and Brian Henderson (ed.), The Human Microbiota And Chronic Disease- Dysbioses As A Cause Of Human Pathology. Chapter 30, 1st Edition. Wiley Blackwell, 2015

Brown K., Molcan E., Rajendiran E., Baker J., Nusrat A., Ruscheinsky S., & D.L. Gibson (2013) Oxidative stress in gastrointestinal disease. Systems biology of free radicals and anti-oxidants. Editor: I. Laher, Springer-Verlag, Germany.